The Nobel Prize for physiology or medicine was given Monday morning to three scientists who've uncovered the 'inner GPS' in our brains that helps us find our way through the world around us, identifying where we are, where we've been and how to get back there again. From the Nobel committee's poetic announcement:
The discoveries of John O'Keefe, May‐Britt Moser and Edvard Moser have solved a problem that has occupied philosophers and scientists for centuries - how does the brain create a map of the space surrounding us and how can we navigate our way through a complex environment?
The answers have some direct implications for how we understand diseases like Alzheimer's that rob people of their spatial memory. But they also have some fascinating implications for perfectly healthy people, too, and for the way we design spaces - from individual buildings to neighborhoods and whole transportation networks - that we move through daily. While the first story is clearly the province of scientists and doctors, the second is very much of interest to urban planners, architects and cartographers.
For them, the evolving science of your 'inner GPS' could help create places that aren't so confusing - or help us understand why so many of the places we've already built (medical complexes, train stations, downtown Atlanta) are.
First, a very quick sketch of what the newest Nobel laureates have taught us about our brains (and the brains of rats): Back in 1971, O'Keefe discovered nerve cells in rats that activated each time the animals passed by a particular location in a room. When the rats were in one corner, certain cells in their brains activated; when they were in a different part of the room, other cells lit up. O'Keefe called these 'place cells,' and research since his initial discovery suggests that humans have them, too. They help us construct mental maps of space, recognizing the difference between one street corner and the next, between your cubicle and your coworker's. The Mosers (they're married) much more recently added to this the discovery of 'grid cells' that, along with place cells, allow us to determine our position in the world and to navigate through it.
All of this inner navigational work happens without any conscious effort on our part. And yet actual navigation is a real-world challenge most of us wrestle with every day. When you're wandering through a hospital, how do you find the right doctor's office? When you're walking through an unfamiliar city, how do you find your way back to your hotel? In a world where so many of us now use literal GPS systems - with smartphones or in-car navigation screens - are we outsourcing our mental maps to machines? As Sarah Goodyear has explained, for instance, children who are driven everywhere (instead of walking) often don't know where they're going.
In the world of architecture, there's now research underway to determine if all this new neuroscience could help design hospitals where people are less likely to get lost. In many cities, local governments are now deploying the science (and art) of 'wayfinding,' creating street signs and cues that might more intuitively help people find their way through baffling environments (and toward, say, the train station or nearest public bathroom).
Scientists are also learning a lot about the external cues - sights, smells and sounds around us - that influence all this internal mapping in our brains. Perhaps this might ultimately tell us something about which kinds of environments aid or tax our brains more: chaotic cities or quiet suburbs, visually stimulating neighborhoods, or cookie-cutter subdivisions?
Mayank Mehta, a neurophysicist at UCLA who has studied place cells, raised a provocative issue when I talked to him about all of this last year. Evolutionarily speaking, our brains evolved to understand space and navigation moving at a slow speed - while walking. But now, most of us travel, navigate and process environments every day by car (or in even more disorienting environments like subway systems). So how does that change the brain's ability to understand space? 'The fastest we learned to process the world go by was the fastest a human could run,' Mehta told me. 'In a car, the world goes way faster than that.'
It's too soon to say what that means for our internal maps (and the frustration we experience moving through the world). But these questions broached by the research of neuroscientists could influence the way we think about building better environments in the real world.
Entities 0 Name: O'Keefe Count: 2 1 Name: Moser Count: 1 2 Name: Mayank Mehta Count: 1 3 Name: Edvard Moser Count: 1 4 Name: Sarah Goodyear Count: 1 5 Name: UCLA Count: 1 6 Name: Atlanta Count: 1 7 Name: John O'Keefe Count: 1 8 Name: Mehta Count: 1 Related 0 Url: http://ift.tt/1xVgZGd Title: The 2014 Nobel Prize in Physiology or Medicine - Press Release Description: 2014-10-06 The Nobel Assembly at Karolinska Institutet has today decided to award The 2014 Nobel Prize in Physiology or Medicine with one half to John O´Keefe and the other half jointly to May-Britt Moser and Edvard I. Moser for their discoveries of cells that constitute a positioning system in the brain How do we know where we are?
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